De Soto Visit one of the local restaurants in De Soto, Missouri today! Cafe' 21 48 Jefferson Square, De Soto, MO 63020 Cafe' Smoke N Pi 12636 Hwy 21, De Soto, MO 63020 Coyol Mexican Bar & Grill 12967 State Route 21, De Soto, MO 63020 El Lobo Rojo 106 North Main St, De Soto, MO 63020 Fat Boy's Saloon & Grill 301 East Main St, De Soto, MO 63020 Granny Franny's Diner 3191 Flucom Road, De Soto, MO 63020 Junction Cafe' 106 South Main, De Soto, MO 63020 Just Be Kind Cafe' 426 South Main, De Soto, MO 63020 LaChance Vineyards 12237 Peter Moore Ln, De Soto, MO 63020 Proud Supporter and Member of the JCTC Pogolino's 530 North Second St, De Soto, MO 63020
